Frank J Brooks

Frank J Brooks
Frank J Brooks
  • Research Assistant Professor


  • Ph.D. in Physics, Washington University in St. Louis, 2008
  • M.Sc. in Physics, University of Missouri, 2001
  • B.A. in Mathematics, University of St. Louis , 1999
  • A.A. in Mathematics, St. Louis Community College at Florissant Valley, 1996

Academic Positions

  • Research Assistant Professor, Bioengineering, University of Illinois Urbana-Champaign, 2019 - present
  • Research Assistant Professor, Department of Biomedical Engineering, Washington University in Saint Louis, 2017-2019
  • Research Instructor, Department of Radiology, Washington, 2014-2017
  • Research Instructor, Department of Radiation Oncology, Washington, 2013-2014
  • Postdoctoral Researcher, Department of Radiation Oncology, Washington, 2010-2013
  • Postdoctoral Researcher, Department of Physics, Washington University in Saint, 2008-2009
  • Instructor, Washington University in Saint Louis, (Physics, Calculus, Python Programming), 2009, 2012, 2015-2016
  • Instructor, St. Louis Community College at Florissant Valley (Calculus, Physics, Linear Algebra), 2002-2003, 2006, 2008-2010

Other Professional Activities

  • Reviewer for: IEEE-Transactions on Medical Imaging, Journal of Medical Imaging, Medical Physics, Nature: Scientific Reports, Journal of Nuclear Medicine, Nuclear Medicine Communications, Pattern Recognition Letters, Physica Medica, Journal of the Royal Statistical Society

Professional Societies

  • American Statistical Association

Service on Department Committees

  • Authored an Investment for Growth Proposal which was recommended for funding to develop the online 'AI in Medicine' course.
  • Faculty Search Committee, 2020

Service on College Committees

  • Carle - Illinois AI Working Group Member since 2020

Service on Campus Committees

  • COVID-19 Research Oversight Committee (C-ROC)
  • University of Illinois Faculty Senate 2021 - 2023

Selected Articles in Journals

  • Bhadra S, Kelkar V, Brooks FJ and Anastasio MA, "Assessing Regularization in Tomographic Imaging via Hallucinations in The Null Space", Proceedings of SPIE on Medical Imaging (2020).
  • Zhou W, Bhadra S, Brooks FJ, Li H and Anastasio MA, "Progressively-Growing AmbientGANs For Learning Stochastic Object Models From Imaging Measurements", Proceedings of SPIE on Medical Imaging (2020).
  • Brooks FJ, Gunsten SP, Vasireddi SK, Brody SL, Anastasio MA: Using the Image Texture Observed in X-ray Phase-contrast-enhanced Projection Images of in vivo Mouse Lungs to Predict Inflation Pressure. Phys Reports: 7(16) e14208 (2019)
  • Chen DL, Huang HJ, Byers DE, Shifren A, Engle JT, Arentson E, Kemp D, Phillips S, Fujiwara H, Scherrer DE, Spayd KJ, Brooks FJ, Pierce RA, Castro M, Isakow W: The Peroxisome Proliferator-Activated Receptor Agonist Pioglitazone and 5-Lipoxygenase Inhibitor Zileuton Have No Effect on Lung Inflammation in Healthy Volunteers as Detected by Positron Emission Tomography PLoS One 13(2): e0191783 (2017)
  • Michel LS, Dyroff S, Brooks FJ, Spayd KJ, Lim S, Engle JT, Phillips S, Tan B, Wang-Gillam A, Bognar C, Chu W, Zhou D, Mach RH, Laforest R, Chen DL: Imaging poly(ADP-ribose) polymerase activity in cancer with positron emission tomography: Preclinical assessment and first-in-human studies. Radiology 282:453-463 (2017)
  • Brooks FJ, Grigsby PW: Low-order non-spatial effects dominate second-order spatial effects in the texture quantifier analysis of 18F-FDG-PET images PLoS ONE 10(2): e0116574 (2015)
  • Brooks FJ, Grigsby PW: The Effect of Small Tumor Volumes on Studies of Intra-tumoral Heterogeneity of Tracer Uptake J Nuc Med 55:37-42 (2014)
  • Brooks FJ, Grigsby PW: FDG uptake heterogeneity in FIGO IIb cervical carcinoma does not predict pelvic lymph node involvement Radiat Oncol 8:294 (2013)
  • Brooks FJ: Area under the cumulative SUV volume histogram is not a viable metric of intratumoral metabolic heterogeneity: further comments [Letter-to-the-editor]. Eur J Nucl Med Mol Imaging. 40(12):1926-1927 (2013)
  • Brooks FJ: On some misconceptions about tumor heterogeneity quantification [Letter-to-the-editor]. Eur J Nucl Med Mol Imaging. 40(8):1292-4 (2013)
  • Brooks FJ, Grigsby PW: Quantification of Heterogeneity Observed in Medical Images. BMC Med Imaging 13(1):7 (2013)
  • Brooks FJ, Grigsby PW: Current Measures of Metabolic Heterogeneity Within Cervical Cancer Do Not Predict Disease Outcome. Radiat Oncol 6:69 (2011)
  • Brooks FJ, Carlsson AE: Actin Polymerization Overshoots Induced by Plus-end Capping. Phys Biol 7:016008 (2010)
  • Brooks FJ, Carlsson AE: Nonequilibrium Actin Polymerization Treated by a Truncated Rate-equation Method. Phys Rev E 79:031914 (2009)
  • Brooks FJ, Carlsson AE: Actin Polymerization Overshoots and ATP Hydrolysis as Assayed by Pyrene Fluorescence. Biophys J 95(3) 1050-1062 (2008)