Caroline Cvetkovic

Primary Research Area

• Cell and tissue engineering - Regenerative tissue engineering

Research Areas

• Microfabrication
• Regenerative tissue engineering

Chapters in Books

• Cvetkovic C, Ko E, Kaufman C, Grant L, Gillette M, Kong H, Bashir R. (2018). “Rapid prototyping of soft bioactuators,” in 3D Bioprinting in Regenerative Engineering: Principles and Applications, 1st ed., A. Khademhosseini and G. Camci-Unal, Eds. Taylor & Francis.

Selected Articles in Journals

• Cvetkovic C, Patel R, Hogan MK, Shetty A, Anderson M, Basu N, Ramesh S, Sardar D, Ward ME, Deneen B, Horner PJ, Krencik R. (2022). Assessing Gq-GPCR–induced human astrocyte reactivity using bioengineered neural organoids. J Cell Biol, 221 (4): e202107135.
• Zinger A*, Cvetkovic C*, Sushnitha M, Naoi T, Baudo G, Anderson M, Shetty A, Basu N, Tasciotti E, Amit M, Xie T, Taraballi F, Krencik R. (2021). Humanized Biomimetic Nanovesicles for Neuron Targeting. Adv Sci, 8(19):e2101437.
• Sardar D, Lozzi B, Woo J, Huang T, Cvetkovic C, Creighton C, Krencik R, Deneen B. (2021). Mapping Astrocyte Transcriptional Signatures in Response to Neuroactive Compounds. Int J Mol Sci, 22(8), 3975.
• Kaufman CD, Liu SC, Cvetkovic C, Lee C, Naseri Kouzehgarani G, Gillette R, Bashir R, Gillette MU. (2020). Emergence of Functional Neuromuscular Junctions in an Engineered, Multicellular Spinal Cord-Muscle Bioactuator. APL Bioengineering, 4(2):026104. Cover Image.
• Grant L, Raman R, Cvetkovic C, Ferrall-Fairbanks MC, Pagan-Diaz GJ, Hadley P, Ko E, Platt MO, Bashir R. (2019). Long-Term Cryopreservation and Revival of Tissue-Engineered Skeletal Muscle. Tissue Eng A, 25(13-14):1023-1036.
• Cvetkovic C, Basu N, Krencik R. (2018). Synaptic Microcircuit Modeling with 3D Cocultures of Astrocytes and Neurons from Human Pluripotent Stem Cells. Journal of Visualized Experiments, 138.
• Pagan-Diaz GJ, Zhang C, Grant L, Kim Y, Aydin O, Cvetkovic C, Ko E, Solomon E, Hollis J, Kong H, Saif T, Gazzola M, Bashir R. (2018). Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines. Adv. Funct. Mater, 28(23):1801145.
• Lu L, Yang Z, Meacham K, Cvetkovic C, Corbin EA, […], Bashir R, Gereau RW IV, Sheng X, Rogers JA. (2018). Biodegradable Monocrystalline Silicon Photovoltaic Microcells as Power Supplies for Transient Biomedical Implants. Advanced Energy Materials, 8(16):1703035.
• Krencik R, Seo K, Van Asperen J, Basu N, Cvetkovic C, Barlas S, Chen R, Ludwig C, Wang C, Ward ME, Gan L, Horner PJ, Rowitch DH, Ullian EM. (2017). Systematic three-dimensional coculture rapidly recapitulates interactions between human neurons and astrocytes. Stem Cell Reports, 9(6):1745-1753.
• Melhem M, Park J, Knapp L, Reinkensmeyer L, Cvetkovic C, Flewellyn J, Lee M, Jensen T, Bashir R, Kong H, Schook L. (2017). 3D printed stem cell-laden, microchanneled hydrogel patch for the enhanced release of cell-secreting factors and treatment of myocardial infarctions. ACS Biomater. Sci. Eng. 3(9):1980-1987.
• Cvetkovic C*, Ferrall-Fairbanks MC*, Ko E, Grant L, Kong H, Platt MO, Bashir R. (2017). Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines. Scientific Reports, 7(1):3775.
• Cvetkovic C, Rich MH, Raman R, Kong H, Bashir R. (2017). A 3D Printed Platform for Modular Neuromuscular Motor Units. Microsystems and Nanoengineering, 3(1):17015.
• Raman R, Grant L, Seo Y, Cvetkovic C, Gapinske M, Palasz A, Dabbous H, Kong H, Perez Pinera P, Bashir R. (2017). Damage, Healing, and Remodeling in Optogenetic Skeletal Muscle Bioactuators. Adv Healthcare Materials, 6(12):1700030. Cover Image.
• Raman R, Cvetkovic C, Bashir R. (2017). A Modular Approach to Design, Fabrication, and Characterization of Muscle-Powered Biological Machines. Nature Protocols, 12(3), 519-533. Cover Image.
• Raman R, Cvetkovic C, Uzel SGM, Platt, RJ, Sengupta P, Kamm RD, Bashir R. (2016). Optogenetic Skeletal Muscle-Powered Adaptive Biological Machines. PNAS, 113(13), 3497-3502.
• Cvetkovic C*, Raman R*, Chan V, Williams BJ, Tolish M, Bajaj P, Sakar MS, Asada HH, Saif MTA, Bashir R. (2014). Three-Dimensionally Printed Biological Machines Powered by Skeletal Muscle. PNAS, 111(28), 10125-10130.

Patents

• Bashir R, Raman R, Cvetkovic C. (2021). “Muscle-Powered Biological Machines.” US Patent 10,906,169 B1.
• Bashir R, Chan V, Raman R, Cvetkovic C. (2018). “Locomotive Biological Machines.” US Patent 10,156,560.

Teaching Honors

• Excellence in Mentoring Award – Houston Methodist Association for Postdoctoral and Trainee Affairs (MAPTA), National Postdoctoral Fellow Appreciation Week, 2020

Research Honors

• 3D Imaging Contest Feature – Cell Picture Show, CellPress, 2020
• People’s Choice Winner and Juror's Choice Winner – NeuroArt Image Contest, MBF Bioscience, 2020
• Neural Control of Organ Degeneration and Regeneration (NeuralCODR) Fellowship – Center for Neuroregeneration, Houston Methodist Research Institute, 2020-2021

Other Honors

• Career Development Award – Biomedical Engineering Society (BMES), 2019
• Trainee Professional Development Award – Society for Neuroscience (SfN), 2018