Michael L. Oelze

Michael L Oelze
(217) 333-9226
4251 Beckman Institute
Associate Professor
(217) 333-9226
4251 Beckman Institute

Research Topics

  • Bioimaging at Multi-Scale


  • PhD in Physics, University of Mississippi, 2000

For more information

Research Topics

  • Bioimaging at Multi-Scale

Research Interests

  • Acoustic Communications
  • Ultrasound therapy
  • Coded Excitation and Ultrasound
  • Ultrasound Computed Tomography
  • Bioeffects of ultrasound
  • Treatment monitoring using ultrasound
  • Cancer diagnosis using ultrasound
  • Quantitative ultrasound imaging
  • Ultrasound backscatter microscopy

Research Statement

Professor Oelze's research deals with several aspects of ultrasound/tissue interaction including: cancer detection using quantitative ultrasound, ultrasound microscopy, bioeffects of ultrasound, ultrasound-based therapies and coded excitation. Professor Oelze is using quantitative ultrasound techniques to analyze ultrasonic backscatter for breast cancer and thyroid cancer detection and for detection and grading of fatty liver disease. Professor Oelze has examined the effects of ultrasound on hemorrhaging of lung tissue. Dr. Oelze is also studying the use of very high frequency ultrasound for experiments in ultrasound backscatter microscopy. Dr. Oelze has been studying inverse scattering techniques to create tomographic reconstructions of the sound speed, density and attenuation of materials. Dr. Oelze is researching means to estimate the concentration of ultrasound contrast agents in vivo from the backscattered signals. Dr. Oelze has developed a novel coded excitation technique combined with pulse compression to double the bandwidth of an ultrasonic imaging system. The additional bandwidth can be used to improve spatial resolution, improve contrast resolution, and/or improve the estimation of scatterer properties. Dr. Oelze is also interested in using coded excitation to improve harmonic imaging in ultrasound. Dr. Oelze is working on a project involving ultrasound-activated microbubbles to enhance cancer therapy. Finally, Dr. Oelze is working on techniques to stage, monitor, and assess high-intensity focused ultrasound treatment of solid tumors. The technique is based on using quantitative ultrasound imaging to detect tissue changes due to temperature rise in tissues, and assessing noninvasively the effects of thermal ablation and hyperthermia on tissues. Dr. Oelze is also interested in monitoring therapy in tumors and in novel ultrasonic therapies for cancer treatment.


University of Illinois at Urbana-Champaign
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1406 W. Green St
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