Stephen Allen Boppart

Stephen Allen Boppart
Abel Bliss Professor of Engineering and Director of Imaging at Illinois
(217) 244-7479
4351 Beckman Institute

Research Topics

  • Bioimaging at Multi-Scale


  • M.D. Medicine Harvard Medical School June 2000
  • Ph.D. Medical and Electrical Engineering Massachusetts Institute of Technology June 1998

Academic Positions

  • Director, Imaging at Illinois; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, August 2008-November 2015
  • Full Professor (50%), Department of Electrical and Computer Engineering; Full Professor (50%), Department of Bioengineering; Clinical Professor (0%), Department of Internal Medicine; Research Professor (0%), Micro and Nanotechnology Laboratory; Research Professor (0%), Institute for Genomic Biology; Full Professor (0%), Neuroscience Program; Full Professor (0%), Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

For more information

Research Topics

  • Bioimaging at Multi-Scale

Research Interests

  • Optical Diagnostics of Cancer
  • Medical Engineering
  • Image-Guided Surgery
  • Optical Coherence Tomography
  • Lasers in Medicine and Biology
  • Optical Biomedical Imaging

Research Statement

My interdisciplinary research group combines the fields of engineering, medicine, and biology to develop novel optical biomedical imaging technologies and translate these for biological discovery and clinical applications. Biophotonics, the application of light in medicine, biology, and biotechnology applications, enables us to develop innovative technologies to detect disease at early stages, when it is most amenable to treatment.

Selected Articles in Journals

  • Graf BW, Chaney EJ, Marjanovic M, Adie SG, De Lisio M, Valero MC, Boppart MD, Boppart SA. Long-term time-lapse multimodal intravital imaging of regeneration and bone-marrow-derived cell dynamics in skin. Technology, 1:1-12, DOI:10.1142/S2339547813500027, 2013.
  • Graf BW, Bower A, Chaney EJ, Marjanovic M, Adie SG, De Lisio M, Valero MC, Boppart MD, Boppart SA. In vivo multimodal microscopy for detecting bone-marrow-derived cell contribution to skin regeneration. (Featured on Cover) Journal of Biophotonics, 7:96-102, 2014.
  • Ahmad A, Shemonski ND, Adie SG, Kim H, Hwu W-M, Carney PS, Boppart SA. Real-time in vivo computed optical interferometric tomography. Nature Photonics, 7:444-448, 2013.
  • Nguyen CT, Jung W, Kim J, Chaney EJ, Novak M, Stewart CN, Boppart SA. Non-invasive in vivo optical detection of biofilm in the human middle ear. Proceedings of the National Academy of Sciences, USA, 109:9529-9534, 2012.
  • Adie SG, Graf BW, Ahmad A, Carney PS, Boppart SA. Computational adaptive optics for broadband optical interferometric tomography of biological tissue. Proceedings of the National Academy of Sciences, USA, 109:7175-7180, 2012.
  • Jung W, Kim J, Jeon M, Chaney EJ, Stewart CN, Boppart SA. Handheld optical coherence tomography scanner for primary care diagnostics. IEEE Transactions on Biomedical Engineering, Invited Cover Figure, 58:741-744, 2011.
  • Chowdary PD, Benalcazar WA, Jiang Z, Chaney EJ, Marks DL, Gruebele M, Boppart SA. Molecular histopathology by spectrally-reconstructed nonlinear interferometric vibrational imaging. Cancer Research (Invited Cover Figure), 70:9562-9569, 2010.
  • Nguyen FT, Zysk AM, Chaney EJ, Kotynek JG, Oliphant UJ, Bellafiore FJ, Rowland KM, Johnson PA, Boppart SA. Intraoperative evaluation of breast tumor margins with optical coherence tomography. Cancer Research (Invited Cover Figure), 69:8790-8796, 2009.
  • T.S. Ralston, D.L. Marks, P.S. Carney, S.A. Boppart, "Interferometric Synthetic Aperture Microscopy," Nature Physics, 3:129-134, 2007.
  • C. Xi, D. L. Marks, D. S. Parikh, L. Raskin, and S. A. Boppart, "Structural and Functional Imaging of Three-Dimensional Microfluidic Mixers Using Optical Coherence Tomography." Proceedings of the National Academy of Science, USA, 101:7516-7521, 2004.
  • D. L. Marks, and S. A. Boppart, "Nonlinear Interferometric Vibrational Imaging," Physics Review Letters, 92:123905, 2004.
  • Boppart SA, Luo W, Marks DL, and Singletary K, "Optical Coherence Tomography: Feasibility for Basic Research and Image-Guided Surgery of Breast Cancer," Breast Cancer Research and Treatment, vol. 84, pp. 85-97, 2004.
  • Boppart SA, Bouma BE, Pitris C, Southern JF, Brezinski ME, Fujimoto JG, "In Vivo Cellular Optical Coherence Tomography Imaging," Nature Medicine, vol. 4, no. 7, pp. 861-864, 1998.

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