Jozien Goense

Primary Research Area

• Biomedical imaging - Functional MRI

Research Areas

• Functional MRI
• MRI
• Systems biology

Chapters in Books

• Nothnagel N, Huber L, Goense J (2023). Sequences and contrasts for non-BOLD fMRI. In: ‘Ultra high field Neuro MRI’. Elsevier series on ‘Advances in Magnetic Resonance Technology and Applications’. Eds. B Poser, M Guye, K Markenroth Bloch
• Zaldivar D, Logothetis NK, Rauch A, Goense J (2017). Pharmaco-based MRI and neurophysiology in non-human primates. In: In vivo Neuropharmacology and Neurophysiology. Springer Neuromethods Series. Ed. A Philippu
• Bartels A, Goense J, Logothetis NK (2012) An introduction to functional Magnetic Resonance Imaging (fMRI) and the origin of the blood oxygen level dependent (BOLD) signal. In: Handbook of Neural Activity Measurement. Eds. Brette R & Destexhe A. Cambridge University Press
• Goense J, Logothetis NK (2010) Physiological basis of the BOLD signal. In: Integrating EEG and fMRI: recording, analysis and integration. Oxford University Press, Eds. M Ullsperger & S Debener

Selected Articles in Journals

• Nothnagel N, Morgan AT, Muckli L, Goense J (2025). Revealing layer-specific cortical activity in human M1 using high-resolution line-scanning fMRI. Imaging Neuroscience 3: 00477
• Bohraus Y, Merkle H, Logothetis NK, Goense J (2023). Laminar differences in functional oxygen metabolism in monkey visual cortex measured with calibrated fMRI. Cell Reports 42(11): 113341
• Sri S, Greenstein A, Granata A, Collcutt A, Jochems A, McColl B, Díaz Castro B, Webber C, Arteaga Reyes C, Hall C, Lawrence C, Hawkes C, Pegasiou-Davies C-M, Gibson C, Crawford C, Smith C, Vivien D, McLean F, Wiseman F, Brezzo G, Lalli G, Pritchard H, Markus H, Bravo-Ferrer I, Taylor J, Leiper J, Berwick J, Gan J, Gallacher J, Moss J, Goense J, McMullan L, Work L, Turner L, Stringer M, Ashford M, Abulfadl M, Conlon N, Malhotra P, Bath P, Canter R, Brown R, Ince S, Anderle S, Young S, Quick S, Szymkowiak S, Hill S, Allan S, Wang T, Quinn T, Procter T, Farr TD, Zhao X, Yang Z, Hainsworth AH*,Wardlaw JM* (2023). A Multi-disciplinary Commentary on Preclinical Research to investigate Vascular Contributions to Dementia. Cerebral Circulation - Cognition and Behavior 5: 100189
• Huber L, Poser BA, Bandettini PA, Arora K, Wagstyl K, Cho S, Goense J, Nothnagel N, Morgan AT, van den Hurk J, Mueller AK, Reynolds RC, Glen DR, Goebel R, Gulban OF (2021) LayNii: A software suite for layer-fMRI. NeuroImage 237: 118091
• Huber L, Finn ES, Handwerker DA, Bönstrup M, Glen D, Kashyap S, Ivanov D, Petridou N, Marrett S, Goense J, Poser BA, Bandettini PA (2020) Sub-millimeter fMRI reveals multiple topographic digit representations that form action maps in human motor cortex. NeuroImage 208: 116463
• Zaldivar D, Rauch A, Logothetis NK, Goense J (2018) Two distinct profiles of fMRI and neurophysiological activity elicited by acetylcholine in visual cortex. PNAS 115(5): E12073-12082
• Grent-’t Jong T, Gross J, Goense J, Wibral M, Gajwani R, Gumley AI, Lawrie S, Schwannauer M, Schultze-Lutter F, Navarro Schröder T, Koethe D, Leweke FM, Singer W, Uhlhaas PJ (2018) Resting-state gamma-band power alterations in schizophrenia reveal functional E/I-balance abnormalities across illness-stages. eLife 7: e37799
• Goense J (2018) Resolving memory circuits with layer-dependent fMRI. Neuron 99: 1107-1109
• Horsburgh K, Wardlaw J, van Agtmael T, Allan S, Ashford M, Bath P, Brown R, Berwick J, Cader Z, Carare R, Davies JB, Duncombe J, Farr TD, Fowler J, Goense J, Granata A, Hall C, Hainsworth A, Harvey A, Hawkes C, Joutel A, Kalaria R, Kehoe P, Lawrence C, Lockhart A, Love S, MacLeod M, Macrae IM, Markus HS, McCabe C, McColl B, Meakin P, Miller A, Nedergaard M, O’Sullivan M, Quinn T, Rajani R, Saksida L, Smith C, Smith K, Touyz R, Trueman R, Wang T, Williams A, Williams S, Work L (2018) ‘Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology’ workshop proceedings. Clinical Science 132: 851-868
• Zaldivar D, Goense J, Lowe S, Logothetis NK, Panzeri S (2018) Dopamine is signalled by mid-frequency oscillations and boosts output layers visual information in visual cortex. Current Biology 28: 224-235
• Huber L, Handwerker DA, Jangraw DC, Chen G, Hall A, Stüber C, Gonzalez-Castillo J, Ivanov D, Marrett S, Guidi M, Goense J, Poser BA, Bandettini PA (2017) High-resolution CBV-fMRI allows mapping of laminar activity and connectivity of cortical input and output in human M1. Neuron 96: 1253-1263
• Goense J, Bohraus Y, Logothetis NK (2016) High-resolution fMRI: implications for BOLD models. Frontiers Comput NeuroSci 10: 66
• Huber L, Goense J, Kennerley AJ, Trampel R, Guidi M, Reimer E, Ivanov D, Neef N, Gauthier CJ, Turner R, Möller HE (2015) Cortical lamina-dependent blood volume changes in human brain at 7T. NeuroImage 107: 23-33
• Zaldivar D, Rauch A, Whittingstall K, Logothetis NK, Goense J (2014) Dopamine-induced dissociation of BOLD- and neural activity in macaque visual cortex. Current Biology 24: 2805-2811
• Huber L, Goense J, Kennerley AJ, Ivanov D, Krieger SN, Lepsien J, Trampel R, Turner R, Möller HE (2014) Investigation of the neurovascular coupling in positive and negative BOLD responses in human brain at 7T. Neuroimage 97: 349-362
• Goense J, Merkle H, Logothetis NK (2012) High-resolution fMRI reveals laminar differences in neurovascular coupling between positive and negative BOLD responses. Neuron 76(3): 629-63
• Von Pföstl V, Li J, Zaldivar D, Goense J, Zhang X, Serr N, Logothetis NK, Rauch A (2012) Effects of lactate on the early visual cortex of non-human primates, investigated by pharmaco-MRI and neurochemical analysis. NeuroImage 61(1): 98-105
• Goense J, Whittingstall K, Logothetis NK (2012) Neural- and BOLD responses across the brain. Wiley Interdisciplinary Reviews Cognitive Science 3(1): 75-86
• Stoewer S, Goense J, Keliris GA, Bartels A, Logothetis NK, Duncan J, Sigala N (2012) An analysis approach for high field fMRI data from awake non-human primates. PLoS one 7(1): e29697
• Ku S-P, Tolias AS, Logothetis NK, Goense J (2011) fMRI of the face-processing network in the ventral temporal lobe of awake and anesthetized macaques. Neuron 70(2): 352-362
• Stoewer S, Goense J, Keliris GA, Bartels A, Logothetis NK, Duncan J, Sigala N (2011) Realignment strategies for awake-monkey fMRI data. Magnetic Resonance Imaging 29(10): 1390-1400
• Logothetis NK, Augath M, Murayama Y, Rauch A, Sultan F, Goense J, Oeltermann A, Merkle H (2010) The effects of electrical microstimulation on cortical signal propagation. Nature NeuroScience 13(10): 1283-1291
• Goense J, Logothetis NK, Merkle H (2010) Flexible, phase-matched, linear receive arrays for high field MRI in monkeys. Magnetic Resonance Imaging 28(8): 1183-1191
• Stoewer S, Ku S-P, Goense J, Logothetis NK, Duncan J, Sigala N (2010) Frontoparietal activity with minimal decision and control in the awake macaque at 7T. Magnetic Resonance Imaging 28(8): 1120-1128
• Goense J, Whittingstall K, Logothetis NK (2010) Functional magnetic resonance imaging of awake behaving macaques. Methods 50: 178-188
• OpdeBeeck H, DiCarlo JJ, Goense J, Grill-Spector K, Tanafuji M, Tsao D (2008) Fine-scale spatial organization of face and object selectivity in the temporal lobe: do fMRI, optical imaging, and electrophysiology agree? J Neuroscience 28(46): 11796-11801
• Goense J, Logothetis NK (2008) Neurophysiology of the BOLD fMRI signal in awake monkeys. Current Biology 18: 631-640
• Goense J, Ku S-P, Merkle H, Tolias AS, Logothetis NK (2008) fMRI of the temporal lobe of the awake monkey at 7T. NeuroImage 39: 1081-1093
• Zappe AC, Pfeuffer J, Merkle H, Logothetis NK, Goense J (2008) The effect of labeling parameters on perfusion-based fMRI in nonhuman primates. J Cereb Blood Flow Metab 18(11): 2666-2673
• Goense J, Zappe AC, Logothetis NK (2007) High-resolution fMRI of monkey V1. Magnetic Resonance Imaging 25: 740-747
• Goense J, Logothetis NK (2006) Laminar specificity in monkey V1 using high resolution SE-fMRI. Magnetic Resonance Imaging 24: 381-392

Articles in Conference Proceedings

• Morgan AT, Nothnagel N, Goense J, Muckli L (2020) High resolution line scanning reveals distinct response properties across human cortical layers. Proc. International Society for Magnetic Resonance in Medicine
• Huber L, Poser BA, Bandettini PA, Arora K, Wagstyl K, Cho S, Goense J, Nothnagel N, Morgan AT, van den Hurk J, Reynolds RC, Glen DR, Goebel R, Gulban OF (2020) LAYNII: A software suite for layer-fMRI. Proc. European Society for Magnetic Resonance and Biology
• Huber L, Poser BA, Bandettini PA, Arora K, Wagstyl K, Cho S, Goense J, Morgan AT, Nothnagel N, Mueller AK, van den Hurk J, Reynolds RC, Glen DR, Goebel R, Gulban OF (2021) LAYNII: A software suite for layer-fMRI. Proc. International Society for Magnetic Resonance in Medicine
• Nothnagel ND, Symon A, Morgan AT, Huber L, Riddell J, Goense J (2021) VASO-fMRI with Nordic-PCA for laminar sensory testing at 7 Tesla. Proc. International Society for Magnetic Resonance in Medicine
• Nothnagel ND, Morgan AT, Symon A, Muckli L, Goense J (2023). Optimized signal saturation for fast functional line scanning of cortical layers. Proc. International Society for Magnetic Resonance in Medicine
• Zaldivar D, Bohraus Y, Logothetis NK, Goense J (2023). Layer dependent changes of neural activity underlying laminar fMRI. Proc. International Society for Magnetic Resonance in Medicine
• Benson J, Majumdar S, Sutton B, Gritton H, Goense J (2025). Perinatal exposure to phthalate mixtures alters structural and functional networks in mouse brain. Proc. International Society for Magnetic Resonance in Medicine

Invited Lectures

• What we can learn from animals that we cannot learn from humans
• Theory: What Neuroscience Insights Can Layer-Specific Activity Provide?
• ‘Laminar fMRI in humans and animals’.
• ‘Laminar specific fMRI at high field’.
• ‘Ultra high resolution fMRI: mesoscopic, mechanistic, multidisciplinary’.
• ‘Neurovascular coupling across cortical layers’.
• ‘Cortical layer specific fMRI at ultra high field’.