Yudu Li

Research Interests

• AI-powered brain mapping
• Magnetic resonance imaging
• Magnetic resonance spectroscopic imaging
• Computational imaging
• Machine learning
• Signal processing

Chapters in Books

• Yao Li, Yudu Li, Zhi-Pei Liang, "Magnetic Resonance Spectroscopic Imaging of Brain Plasticity," in Handbook of Cognitive Enhancement and Brain Plasticity, edited by Aron Barbey. (In revision)

Selected Articles in Journals

• Y. Guan*, Y. Li*, R. Liu, Z. Meng, Y. Li, L. Ying, Y. Du, and Z.-P. Liang, “Subspace model-assisted deep learning for improved image reconstruction,” IEEE Trans. Med. Imaging, 2023, In Press. (*co-first authors)
• Y. Li, Y. Zhao, R. Guo, T. Wang, Y. Zhang, M. Chrostek, W.C. Low, X.-H. Zhu, Z.-P. Liang, and W. Chen, “Machine learning-enabled high-resolution deuterium MR spectroscopic imaging for dynamic metabolic imaging of brain cancer,” IEEE Trans. Med. Imaging, vol. 40, pp. 3879-3890, 2021.
• Y. Li, J. Xiong, R. Guo, Y. Zhao, Y. Li, and Z.-P. Liang, “Improved estimation of myelin water fractions with learned parameter distributions,” Magn. Reson. Med., vol. 86, pp. 2795-2809, 2021.
• Y. Chen, Y. Li*, and Z. Xu, “Improved low-rank filtering of MR spectroscopic imaging data with pre-learnt subspace and spatial constraints," IEEE Trans. Biomed. Eng., vol. 67, pp. 2381-2388, 2019. (*Corresponding Author)
• Y. Li, F. Lam, B. Clifford, and Z.-P. Liang, “A subspace approach to spectral quantification for MR spectroscopic imaging,” IEEE Trans. Biomed. Eng., vol. 64, pp. 2486-2489, 2017. (Highlighted Article)
• Y. Guan, Y. Li, Z. Ke, X. Peng, R. Liu, Y. Li, Y. Du, and Z.-P. Liang, "Learning-assisted Fast Determination of regularization parameter in constrained image reconstruction," IEEE Trans. Biomed. Eng, vol. 71, pp. 2253-2264, 2024.
• Y. Zhao, Y. Li, R. Guo, W. Jin, B. Sutton, C. Ma, G. El Fakhri, Y. Li, J. Luo, Z.-P. Liang, “Accelerated 3D metabolite T1 mapping of the brain using variable-flip-angle SPICE,” Magn Reson Med, In Press.
• R. Guo, S. Yang, H. M. Wiesner, Y. Li, Y. Zhao, Z.-P. Liang, W. Chen, X.-H. Zhu, “Mapping intracellular NAD content in entire human brain using phosphorus-31 MR spectroscopic imaging at 7 Tesla,” Front Neurosci., vol. 18, pp. 1389111, 2024.
• R. Jin, Y. Li, R. K. Shosted, F. Xing, I. Gilbert, J. Perry, J. Woo, Z.-P. Liang, B. P. Sutton, “Optimization of three-dimensional dynamic speech MRI: Poisson-disc under sampling and locally higher-rank reconstruction through partial separability model with regional optimized temporal basis”, Magn. Reson. Med., vol. 91, pp. 61-74, 2024.
• T. Zhang, Y. Zhao, W. Jin, Y. Li, R. Guo, Z. Ke, J. Luo, Y. Li, Z.-P. Liang, “B1 mapping using pre-learned subspaces for quantitative brain imaging”, Magn. Reson. Med., vol. 88, pp. 2198-2207, 2022.
• Z. Meng, R. Guo, T. Wang, B. Bo, Z. Lin, Y. Li, Y. Zhao, X. Yu, D. J. Lin, P. Nachev, Z.-P. Liang, and Y. Li, “Prediction of stroke onset time with joint fast high-resolution magnetic resonance spectroscopic and quantitative T2 mapping”, IEEE Trans. Biomed. Eng., vol. 70, pp. 3147-3155, 2023.
• L. Tang, Y. Zhao, Y. Li, R. Guo, B. Cai, J. Wang, Y. Li, Z.-P. Liang, X. Peng, and J. Luo, “JSENSE-Pro: Joint sensitivity estimation and image reconstruction in parallel imaging using pre-learned subspaces of coil sensitivity functions”, Magn. Reson. Med., vol. 89, pp. 1531-1442, 2023.
• Z. Lin, Z. Meng, T. Wang, R. Guo, Y. Zhao, Y. Li, B. Bo, Y. Guan, J. Liu, H. Zhou, X. Yu, D.J. Lin, Z.-P. Liang, P. Nachev, and Y. Li, “Predicting the onset of ischemic stroke with fast high-resolution 3D MR spectroscopic imaging,” J. Magn. Reson. Imaging, vol. 58, pp. 838-847, 2023. (W.S. Moore Award of ISMRM 2023)
• R. Guo, Y. Li, Y. Zhao, T. Wang, Y. Li, B. Sutton, and Z.-P. Liang, and W. Chen, “Simultaneous mapping of water diffusion coefficients and metabolite distributions of the brain using MR spectroscopic imaging without water suppression,” IEEE Trans. Biomed. Eng., vol. 70, pp. 962-969, 2022.
• T. Zhang, R. Guo, Y. Li, Y. Zhao, Y. Li, and Z.-P. Liang, “T_2^' mapping of the brain from water-unsuppressed 1H-MRSI and TSE data,” Magn. Reason. Med., vol. 88, pp. 2198-2207, 2022.
• Y. Zhao, R. Guo, Y. Li, K.R. Thulborn, and Z.-P. Liang, “High-resolution sodium imaging using anatomical and sparsity constraints for denoising and recovery of novel features,” Magn. Reason. Med., vol. 86, pp. 625-636, 2021. (YIA Award of OCSMRM)
• Z. Meng, R. Guo, Y. Li, Y. Guan, Y. Wang, Y. Zhao, B. Sutton, Y. Li, and Z.-P. Liang, “Accelerating T2 mapping of the brain by integrating deep learning priors with low‐rank and sparse modeling”, Magn. Reson. Med., 85.3 (2021): 1455-1467.
• R. Guo, Y. Zhao, Y. Li, T. Wang, Y. Li, B. Sutton, and Z.-P. Liang, “Simultaneous QSM and metabolic imaging of the brain using SPICE: further improvements in data acquisition and processing”, Magn. Reson. Med., 85.2 (2021): 970-977.
• L. Tang, Y. Zhao, Y. Li, R. Guo, B. Clifford, G. E. Fakhri, C. Ma, Z.-P. Liang, and J. Luo, “Accelerated J-resolved 1H-MRSI with limited and sparse sampling of (k,t_1)-space”, Magn. Reson. Med., vol. 85, pp. 30-41, 2021.
• Y. Li, T. Wang, T. Zhang, Y. Li, R. Guo, Y. Zhao, Z. Meng, Z. Lin, J. Liu, X. Yu, Z.-P. Liang, P. Nachev, “Fast high-resolution metabolic imaging of acute stroke with 3D magnetic resonance spectroscopy”, Brain, 143(11), 3225-3233.
• F. Lam, Y. Li, R. Guo, B. Clifford, and Z.-P. Liang, “Ultrafast magnetic resonance spectroscopic imaging using SPICE with learned subspaces”, Magn. Reson. Med., vol. 83, pp. 377-390, 2020. (Editor’s Picks)
• B. Clifford, Y. Gu, Y. Liu, K. Kim, S. Huang, Y. Li, F. Lam, Z.-P. Liang, X. Yu, “High-resolution dynamic 31P-MR spectroscopic imaging for mapping mitochondrial function.” IEEE Trans. Biomed. Eng. Vol. 67, pp. 2745-2753, 2020. (Highlighted Article)
• R. Guo, Y. Zhao, Y. Li, Y. Li, and Z.‐P. Liang, “Simultaneous metabolic and functional imaging of the brain using SPICE.” Magn. Reson. Med., vol. 82, pp. 1993-2002, 2019.
• F. Lam, Y. Li, B. Clifford, and Z.-P. Liang, “Macromolecule mapping of the brain using ultrashort-TE acquisition and reference-based metabolite removal,” Magn. Reson. Med., vol. 79, pp. 2460-2469, 2017.
• X. Peng, F. Lam, Y. Li, B. Clifford, and Z.-P. Liang, “Simultaneous QSM and metabolic imaging of the brain using SPICE,” Magn. Reson. Med., vol. 79, pp. 13-21, 2017.

Articles in Conference Proceedings

• Y. Li, Y. Guan, Y. Zhao, R. Guo, Y. Li, and Z.-P. Liang, “Integrating subspace learning, manifold learning, and sparsity learning to reconstruct image sequences”, Proc. Intl. Soc. Magn. Reson. Med., 2022, p. 4591. (Magna Cum Laude Paper Award)
• Y. Li, R. Guo, Y. Zhao, Y. Li, and Z.-P. Liang, “Improved myelin water fraction estimation integrating learned probabilistic subspaces and low-dimensional manifolds”, Proc. Intl. Soc. Magn. Reson. Med., 2022, p. 5348
• R. Guo, Y. Li, Y. Zhao, T. Wang, Y. Li, B. Sutton, and Z.-P. Liang, “Simultaneous mapping of water diffusion coefficients and metabolite distributions of the brain using MRSI without water suppression”, Proc. Intl. Soc. Magn. Reson. Med., 2022, p. 2691. (Magna Cum Laude Paper Award)
• R. Guo, Y. Li, Y. Zhao, S. Tafti, A. Anderson, B. Sutton, and Z.-P. Liang, “Rapid whole brain high-resolution MR spectroscopic imaging at 7T”, Proc. Intl. Soc. Magn. Reson. Med., 2022, p. 2697
• Y. Zhao, Y. Li, R. Guo, K. R. Thulborn, and Z.-P. Liang, “Reconstructing high-quality sodium MR images from limited noisy k-space data with model-assisted deep learning”, Proc. Intl. Soc. Magn. Reson. Med., 2022, p. 1872
• Y. Guan, Y. Li, R. Liu, Z. Meng,Y. Li, L. Ying, Y. P. Du, and Z.-P. Liang, “Image reconstruction with subspace-assisted deep learning,” Proc. Intl. Soc. Magn. Reson. Med., 2022, p. 2433.
• R. Liu, Y. Li, Z. Meng, Y. Guan, T. Wang, T. Li, Y. P. Du, and Z.-P. Liang, “Reconstructing T2 maps of the brain from highly sparse k-space data with generalized series-assisted deep learning”, Proc. Intl. Soc. Magn. Reson. Med., 2022, p. 6187
• Y. Li, J. Xiong, R. Guo, Y. Zhao, Y. Li, and Z.-P. Liang, “Improved estimation of myelin water fractions with learned parameter distributions,” Proc. Intl. Soc. Magn. Reson. Med., 2021, p. 2075. (Summa Cum Laude Paper Award)
• Y. Li, Y. Zhao, R. Guo, T. Wang, Y. Zhang, M. Chrostek, W.C. Low, X.-H. Zhu, W. Chen, and Z.-P. Liang, “A marriage of subspace modeling with deep learning to enable high-resolution dynamic deuterium MR spectroscopic imaging,” Proc. Intl. Soc. Magn. Reson. Med., 2021, p. 2524.
• Y. Guan, Y. Li, X. Peng, Y. Li, Y.p. Du, and Z.-P. Liang,"Learn to better regularize in constrained reconstruction," Proc. Intl. Soc. Magn. Reson. Med., 2021, p. 3063.
• Y. Li, Y. Zhao, R. Guo, F. Yu, X.-H. Zhu, W. Chen, and Z.-P. Liang, “Rapid dynamic deuterium MR spectroscopic imaging using deep-SPICE,” Proc. Intl. Soc. Magn. Reson. Med., 2020, p. 3739.
• Y. Li, K. Kim, B. Clifford, R. Guo, Y. Gu, Z.-P. Liang, and X. Yu, “High-resolution dynamic 31P-MRSI of ischemia-reperfusion in rat using low-rank tensor model with deep learning priors,” Proc. Intl. Soc. Magn. Reson. Med., 2020, p. 4538. (Summa Cum Laude Paper Award)
• Y. Li, Y. Guan, Z. Meng, F. Yu, R. Guo, Y. Zhao, T. Wang, Y. Li, and Z.-P. Liang, “An information theoretical framework for machine learning based MR image reconstruction,” Proc. Intl. Soc. Magn. Reson. Med., 2020, p. 3858.
• R. Guo, Y. Li, Y. Zhao, T. Wang, Y. Li, B. Sutton, and Z.-P. Liang, “High-resolution QSM for simultaneous QSM/MRSI,” Proc. Intl. Soc. Magn. Reson. Med., 2020, p. 1891. (Magna Cum Laude Paper Award)
• R. Guo, Y. Li, Y. Zhao, Y. Li, and Z.-P. Liang, “Making SPICE spicier with sparse sampling of (k, t)-space and learned subspaces,” Proc. Intl. Soc. Magn. Reson. Med., 2020, p. 1899. (Magna Cum Laude Paper Award)
• Y. Zhao, Y. Li, J. Xiong, R. Guo, Y. Li, and Z.-P. Liang, “Rapid high-resolution mapping of brain metabolites and neurotransmitters using hybrid FID/SE-J-resolved spectroscopic signals,” Proc. Intl. Soc. Magn. Reson. Med., 2020, p. 721. (Magna Cum Laude Paper Award)
• Z. Meng, Y. Li, R. Guo, T. Wang, Y. Zhao, F. Yu, B. Sutton, Y. Li, and Z.-P. Liang, “Accelerated T2 mapping by integrating two-stage learning with sparse modeling,” Proc. Intl. Soc. Magn. Reson. Med., 2020, p. 5261. (Magna Cum Laude Paper Award)
• Y. Li, R. Guo, Y. Zhao, T. Wang, Z. Meng, Y. Li and Z.-P. Liang, “Rapid high-resolution simultaneous acquisition of metabolites, myelin water fractions, and tissue susceptibility of the whole brain using ‘SPICY’ 1H-MRSI,” Proc. Intl. Soc. Magn. Reson. Med., pp. 754, 2019. (Summa Cum Laude Paper Award)
• Y. Li, R. Guo, Y. Zhao, Y. Chen, B. Clifford, T. Wang, C. Wang, Y. Du, and Z.-P. Liang, “A model-based method for estimation of myelin water fractions,” Proc. Intl. Soc. Magn. Reson. Med., pp. 511, 2019.
• R. Guo, Y. Li, Y. Zhao, Y. Li, and Z.-P. Liang, “Mapping brain neurochemical and functional coupling using dynamic SPICE,” Proc. Intl. Soc. Magn. Reson. Med., pp. 3735, 2019. (Magna Cum Laude Paper Award)
• J. Liu, Y. Li, T. Wang, Z. Meng, K. Xue, R. Guo, Y. Zhao, Y. Du, Q. Chen, Z.-P. Liang, and Y. Li, “Multimodal imaging of brain tumors using high-resolution 1H-MRSI without water suppression,” Proc. Intl. Soc. Magn. Reson. Med., pp. 7739, 2019.
• Y. Zhao, Y. Li, R. Guo, B. Clifford, X. Yu, and Z.-P. Liang, “Accelerating high-resolution semi-LASER 1H-MRSI using SPICE,” Proc. Intl. Soc. Magn. Reson. Med., pp. 683, 2019.
• Y. Li, and Z.-P. Liang, “Constrained image reconstruction using a kernel+sparse model,” Proc. Intl. Soc. Magn. Reson. Med., pp. 657, 2018.
• Y. Li, F. Lam, B. Clifford, R. Guo, X. Peng, and Z.-P. Liang, “Constrained MRSI reconstruction using water side information with a kernel-based method,” Proc. Intl. Soc. Magn. Reson. Med., pp. 540, 2018. (Magna Cum Laude Paper Award)
• Y. Li, F. Lam, R. Guo, B. Clifford, X. Peng, and Z.-P. Liang, “Removal of water sidebands from 1H-MRSI data acquired without water suppression,” Proc. Intl. Soc. Magn. Reson. Med., pp. 288, 2018.
• F. Lam, Y. Li, R. Guo, B. Clifford, X. Peng, and Z.-P. Liang, “Further accelerating SPICE for ultrafast MRSI using learned spectral features,” Proc. Intl. Soc. Magn. Reson. Med., pp. 623, 2018. (Magna Cum Laude Paper Award)
• F. Lam, Y. Li, and Z.-P. Liang, “Spectral quantification for multiple-TE spectroscopy using spectral priors and measured lineshape distortion function,” Proc. Intl. Soc. Magn. Reson. Med., pp. 657, 2018.
• X. Peng, Y. Li, F. Lam, R. Guo, B. Clifford, and Z.-P. Liang, “Constrained dipole inversion for quantitative susceptibility mapping using a “kernel+sparse” model,” Proc. Intl. Soc. Magn. Reson. Med., pp. 3406, 2018.
• Y. Li, F. Lam, B. Clifford, and Z.-P. Liang, “A subspace approach to spectral quantification,” Proc. Intl. Soc. Magn. Reson. Med., pp. 5467, 2017.
• F. Lam, Y. Li, B. Clifford, X. Peng, and Z.-P. Liang, “Simultaneous mapping of brain metabolites, macromolecules and tissue susceptibility using SPICE,” Proc. Intl. Soc. Magn. Reson. Med., pp. 1249, 2017. (Summa Cum Laude Paper Award)
• F. Lam, Y. Li, B. Clifford, and Z.-P. Liang, “Macromolecule mapping with ultrashort-TE acquisition and metabolite spectral prior,” Proc. Intl. Soc. Magn. Reson. Med., pp. 5518, 2017.
• Y. Li, S. Ma, Z. Hu, J. Chen, G. Su, and W. Dou, “Single trial EEG classification applied to a face recognition experiment using different feature extraction methods,” in Conf. Proc. IEEE Eng. Med. Biol. Soc., pp. 7246-7249, 2015.
• Y. Li, Y. Sun, F. Taya, H. Yu, N. Thakor, and A. Bezerianos, “Single trial EEG classification of lower-limb movements using improved regularized common spatial pattern,” in Proc. 7th Int. IEEE/EMBS Conf. Neural Eng., pp. 1056-1059, 2015.

Invited Lectures

• Deep Learning in MRSI

Research Honors

• Summa Cum Laude Paper Award, ISMRM (as the first author) (2023)
• W.S. Moore Award, ISMRM (as the co-author) (2023)
• Young Investigator Award (1st Place), OCSMRM (2023)
• Thomas and Margaret Huang Award for Graduate Research, UIUC (2022)
• Magna Cum Laude Paper Award, ISMRM (as the first author) (2022)
• Best Student Paper Award, EMBC (as the co-author) (2021)
• Summa Cum Laude Paper Award, ISMRM (as the first author) (2021)
• Yunni & Maxine Pao Memorial Fellowship, UIUC (2021)
• Mavis Future Faculty Fellowship, UIUC (2020)
• Rambus Computer Engineering Fellowship, UIUC (2020)
• Shun Lien Chuang Memorial Award for Excellence in Graduate Education, UIUC (2019)
• Yee Fellowship Award, UIUC (2019)
• Summa Cum Laude Paper Award, ISMRM (as the first author) (2019)
• Magna Cum Laude Paper Award, ISMRM (as the first author) (2018)

Public Service Honors

• Distinguished Reviewer Award, IEEE Transactions on Medical Imaging (2023)
• Distinguish Reviewer Awards, Magnetic Resonance in Medicine (2023)