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Charles M Schroeder

Charles M Schroeder
Charles M Schroeder
Assistant Professor
(217) 333-3906
3247 Beckman Institute
Associate Professor
(217) 333-3906
3247 Beckman Institute

Primary Research Area

  • Bio-Micro and Nanotechnology

For more information

Biography

Charles M. Schroeder is a Professor and the Ray and Beverly Mentzer Faculty Scholar in Chemical and Biomolecular Engineering. He is also an Affiliate in the Departments of Chemistry, Materials Science and Engineering, and Bioengineering, and he is a member of the Center for Biophysics and Computational Biology and the Institute for Genomic Biology in Biosystems Design. His research focuses on single molecule studies of polymer dynamics and biological systems, and his recent work has extended the field of single polymer dynamics to new materials. Professor Schroeder has been recognized by several awards, including the Camille Dreyfus Teacher-Scholar Award, an NSF CAREER Award, the Arthur B. Metzner Award from the Society of Rheology, and a Packard Fellowship in Science and Engineering. Professor Schroeder joined the department in 2008. He received his B.S. (1999) in Chemical Engineering from Carnegie Mellon University, followed by an M.S. (2001) and Ph.D. (2004) in Chemical Engineering at Stanford University. He was a postdoctoral fellow at Harvard University and the University of California, Berkeley.

Education

  • Postdoctorate, University of California at Berkeley, 2007-2008
  • Postdoctorate, Harvard University, 2004-2007
  • Ph.D., Stanford University, 2004
  • B.S., Carnegie Mellon University, 1999

Academic Positions

  • Ray and Beverly Mentzer Professor Department of Materials Science and Engineering Department of Chemical & Biomolecular Engineering University of Illinois at Urbana-Champaign, Urbana, IL, 61801 (8/20-present)
  • Co-Leader, Molecular Science and Engineering (Research Theme) Leader, Molecular Design & Engineering (Research Group) Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign, Urbana, IL, 61801 (8/18-present)
  • Professor and Ray and Beverly Mentzer Faculty Scholar Department of Chemical & Biomolecular Engineering University of Illinois at Urbana-Champaign, Urbana, IL, 61801 (8/17-9/19)
  • Visiting Associate, Division of Chemistry and Chemical Engineering California Institute of Technology, Pasadena, CA, 91125 (1/17-5/17)
  • Associate Professor, Department of Chemical & Biomolecular Engineering University of Illinois at Urbana-Champaign, Urbana, IL, 61801 (8/14-8/17)
  • Assistant Professor, Department of Chemical & Biomolecular Engineering University of Illinois at Urbana-Champaign, Urbana, IL, 61801 (8/08-8/14)
  • Postdoctoral Fellow, Department of Chemical Engineering University of California, Berkeley, Berkeley, CA, 94720 (12/07-7/08)
  • Postdoctoral Fellow, Department of Chemistry and Chemical Biology (Xie Group) Harvard University, Cambridge, MA 02138 (11/04-11/07)
  • Graduate Research Assistant, Department of Chemical Engineering Stanford University, Stanford, CA 94305 (3/00-11/04)

Other Professional Employment

  • Research Assistant, Department of Chemical Engineering, Jhon/Tilton Groups, Carnegie Mellon University, Pittsburgh, PA 15213
  • Research Engineer Intern, Photolithography, Fab 15 (Summer 1998), Intel Corporation, Portland, OR 97007
  • Research Engineer Intern, Chemical/Mechanical Polish, Fab 15 (Summer 1999), Intel Corporation, Portland, OR 97007

Journal Editorships

  • Guest Editor, Journal of Rheology, 2019-2022.
  • Guest Editor, Lab on a Chip, 2016.
  • Member, Editorial Board, Scientific Reports, 2019-present.

Professional Societies

  • American Physical Society (GSOFT, DPOLY)
  • American Association for the Advancement of Science (AAAS)
  • Protein Society, 2005
  • Society of Rheology, 2001-present
  • American Institute of Chemical Engineers, 1995-present

Service on University Committees

  • Member, Advising Committee, Undergraduates, Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign
  • Member, Awards Committee, Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign
  • Member, Biophysics Qualifying Exam Committee, Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign
  • Member, Executive Committee, Beckman Institute, University of Illinois at Urbana-Champaign
  • Leader, Molecular Design and Engineering (MDE) Group, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign
  • Co-Leader, Molecular Science and Engineering (MSE) Theme, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

Research Interests

  • Molecular Engineering, Soft Materials, Molecular Rheology, Single Molecule Biophysics

Research Statement

Molecular Bioengineering and Biophysics
Single molecule techniques represent a new paradigm to study biological and physical processes. In our group, we apply novel molecular-based methods to address key problems in biotechnology and soft materials. Specifically, we design and implement integrated microdevices for high-throughput screening of biomolecules for medical analysis, study the action of natural and evolved enzymes at the molecular level, and investigate the non-equilibrium dynamics of soft materials. Our research is highly interdisciplinary and lies at the interface of biology, engineering, and biotechnology.

Integrated Microdevices for Biotechnology
The genomics age has ushered in a wealth of genetic-based information. As we begin to build a molecular-based understanding of human health, there exists a continuing need for miniaturized microdevices for medical analysis. In our research, we are developing novel integrated devices for biotechnology based on the analysis of single molecules with several applications: disease diagnosis, prediction of drug response, and personalized medicine. The goal of this research is to improve human health by developing and demonstrating high-throughput analysis of single DNA molecules and proteins in microdevices.

Molecular Biophysics
Molecular-based understanding of biological mechanisms – including viral infection pathways, enzymatic reactions, or metabolism – is oftentimes the key to precipitating major advances in bioengineering. We use single molecule techniques to study the behavior of biological systems and processes, including catalysis mechanisms by natural and evolved enzyme systems. We are currently developing new screening tools for protein engineering and studying the action of nucleic-acid enzyme processes, including DNA replication. Observation of single proteins and enzymes allows for characterization of real-time dynamics, molecular subpopulations, and heterogeneous biological behavior.

Soft Materials: Polymer Dynamics
Polymers are ubiquitous in modern technology and represent an interesting example of soft matter. Biopolymers such as DNA, RNA, and proteins store vital information in cells and perform essential tasks to ensure survival of an organism; synthetic polymers are commonly encountered in a multitude of industrial applications. In our group, we develop and synthesize new materials and biopolymers and study them at the molecular level. We use fluorescence microscopy to directly observe single polymer conformations in flow and to characterize the individualistic dynamical behavior of polymers under highly non-equilibrium conditions.

Primary Research Area

  • Bio-Micro and Nanotechnology

For more information

Chapters in Books

  • C. M. Schroeder, P. C. Blainey, S. Kim, X. S. Xie, "Hydrodynamic Flow-stretching Assay for Single Molecule Studies of Nucleic Acid-Protein Interactions", in Single Molecule Techniques: A Laboratory Manual, T. Ha and P. Selvin (eds.), Cold Spring Harbor Laboratory Press, 2007.
  • A. Mukherjee and C. M. Schroeder, "Microfluidic Methods in Single Cell Biology", in Microfluidic Methods in Molecular Biology, C. Lu and S. Verbridge (eds.), Springer, 2016.

Selected Articles in Journals

  • C. Pan*, S. K. Tabatabaei*, S. M. H. Tabatabaei Yazdi, A. G. Hernandez, C. M. Schroeder*, O. Milenkovic*, "Rewritable Two-Dimensional DNA-Based Data Storage with Machine Learning Reconstruction", submitted (2021). bioRxiv: DOI: 10.1101/2021.02.22.432304
  • C. Lin, D. Kumar, C. Richter, S. Wang, C. M. Schroeder, V. Narsimhan, "Vesicle Dynamics in Large Amplitude Oscillatory Extensional Flow", submitted (2021). arXiv: 2102.09097
  • Y. Zhou, C. D. Young, K. E. Regan, M. Lee, S. Banik, D. Kong, G. B. McKenna, R. M. Robertson- Anderson, C. E. Sing, C. M. Schroeder, "Dynamics and Rheology of Ring-Linear Blend Semidilute Solutions in Extensional Flow: Single Molecule Experiments", submitted (2021). arXiv: 2101.01222
  • C. D. Young, Y. Zhou, C. M. Schroeder, C. E. Sing, "Dynamics and Rheology of Ring-Linear Blend Semidilute Solutions in Extensional Flow: Modeling and Molecular Simulations", submitted (2021). arXiv: 2011.01386
  • S. Li, H. Yu, B. Li, J. S. Moore, C. M. Schroeder, "Regulating Charge Transport via Electric Field- Induced Reactions in Single Oligophenyl Junctions", submitted (2021).
  • S. Jain, S. Shukla, C. Yang, Y. Wang, X. Xiong, S. Abesteh, M. Lingamaneni, C. M. Schroeder, P. R. Selvin, H. Zhao, "TALEN Outperforms Cas9 in Editing Heterochromatin Target Sites", Nature Communications, 12, 606 (2021).
  • 82. S. Patel, C. D. Young, C. E. Sing, C. M. Schroeder, "Non-monotonic Dependence of Comb Polymer Relaxation on Branch Density in Semi-dilute Solutions", Physical Review Fluids, 5, 121301R (2020).
  • M. Tu, M. Lee, R. M. Robertson-Anderson, C. M. Schroeder, "Direct Observation of Ring Polymer Dynamics in the Flow-Gradient Plane of Shear Flow", Macromolecules, 53, 9406-9419 (2020).
  • D. Mai and C. M. Schroeder, "Single Molecule Studies of Synthetic Polymers", ACS Macro Letters, 9, 1332-1341 (2020).
  • S. Li, H. Yu, X. Chen, A. A. Gewirth, J. S. Moore, C. M. Schroeder, "Covalent Ag-C Bonding Contacts from Unprotected Terminal Acetylenes for Molecular Junctions", Nano Letters, 20, 5490-5495 (2020).
  • D. Kumar, C. M. Richter, C. M. Schroeder, "Double-mode Relaxation of Highly Deformed Vesicles", Physical Review E, 102, 010605R (2020).
  • E. R. Jira, K. Shmilovich, T. S. Kale, A. Ferguson, J. D. Tovar, C. M. Schroeder, "Effect of Core Oligomer Length on the Phase Behavior and Assembly of pi-conjugated Peptides", ACS Applied Ma- terials & Interfaces, 12, 20722-20732 (2020).
  • 76. K. R. Peddireddy, M. Lee, C. M. Schroeder, R. M. Robertson-Anderson, "Viscoelastic Properties of Ring-linear DNA Blends Exhibit Non-monotonic Dependence on Blend Composition", Physical Review Research, 2, 023213 (2020).
  • S. Li, J. Li, H. Yu, S. Pudar, B. Li, J. Rodriguez-Lopez, J. S. Moore, C. M. Schroeder, "Characterizing Intermolecular Interactions in Redox-active Pyridinium-based Molecular Junctions", Journal of Electroanalytical Chemistry, in press (2020).
  • D. Kumar, A. Shenoy, J. C. Deutsch, C. M. Schroeder, "Automation and Flow Control for Particle Manipulation", Current Opinion in Chemical Engineering, 29, 1-8 (2020).
  • H. Yu*, S. Li*, K. E. Schwieter, Y. Liu, B. Sun, J. S. Moore, C. M. Schroeder, "Charge Transport in Sequence-de ned Conjugated Oligomers", Journal of the American Chemical Society, 142, 4852-4861, (2020).
  • K. Peddireddy, M. Lee, Y. Zhou, S. Adalbert, C. M. Schroeder, R. Robertson-Anderson, "Unexpected Entanglement Dynamics in Semidilute Blends of Supercoiled and Ring DNA", Soft Matter, 16, 152-161 (2020).
  • L. Cuculis*, C. Zhao*, Z. Abil, H. Zhao, D. Shukla*, C. M. Schroeder*, "Divalent Cations Enhance TALE DNA-Binding Specicity", Nucleic Acids Research, 48, 1406-1422 (2020).
  • D. Kumar, C. M. Richter, C. M. Schroeder, "Conformational Dynamics and Phase Behavior of Lipid Vesicles in a Precisely Controlled Extensional Flow", Soft Matter, 16, 337-347 (2020).
  • D. Kumar, A. Shenoy, S. Li, C. M. Schroeder, "Orientation Control and Nonlinear Trajectory Tracking of Colloidal Particles using Microfluidics", Physical Review Fluids, 4, 114203 (2019).
  • A. Shenoy, D. Kumar, S. Hilgenfeldt, C. M. Schroeder, "Flow Topology During Multiplexed Particle Manipulation using a Stokes Trap", Physical Review Applied, 12, 054010 (2019).
  • S. Li*, H. Yu*, K. E. Schwieter, K. Chen, B. Li, Y. Liu, J. S. Moore, C. M. Schroeder, "Charge Transport and Quantum Interference in Oxazole-Terminated Conjugated Oligomers", Journal of the American Chemical Society, 141, 16079-16084 (2019).
  • L. Valverde, B. Li, C. M. Schroeder, W. Wilson, "In Situ Photophysical Characterization of - conjugated Oligopeptides Assembled via Continuous Flow Processing", Langmuir, 35, 10947-10957 (2019).
  • C. Boucher-Jacobs, B. Li, C. M. Schroeder, and D. Guironnet, "Solubility and Activity of a Phosphinosulfonate Palladium Catalyst in Water with Di erent Surfactants", Polymer Chemistry, 10, 1988- 1992 (2019).
  • Y. Zhou, K. W. Hsiao, K. E. Regan, D. Kong, G. B. McKenna, R. M. Robertson-Anderson, C. M. Schroeder, "Dynamics of Single Ring Polymers in Semi-dilute Linear Polymer Solutions", Nature Communications, 10, 1753, DOI: 10.1038/s41467-019-09627 (2019).
  • B. Li, H. Yu, E. C. Montoto, Y. Liu, S. Li, K. Schwieter, J. Rodriquez-Lopez, J. S. Moore, C. M. Schroeder, "Intrachain Charge Transport through Conjugated Donor-Acceptor Oligomers", ACS Ap- plied Electronic Materials, 1, 7-12 (2019).
  • Y. Zhou and C. M. Schroeder, "Dynamically Heterogeneous Relaxation of Entangled Polymer Chains", Physical Review Letters, 120, 267801 (2018).
  • S. Li and C. M. Schroeder, "Synthesis and Single Molecule Studies of Thermo-responsive DNA Copolymers", ACS Macro Letters, 7, 281-286 (2018).
  • D. J. Mai, A. Sadaat, B. Khomami, C. M. Schroeder, "Stretching Dynamics of Single Comb Polymers in Extensional Flow", Macromolecules, 51, 1507-1517 (2018).
  • C. M. Schroeder, "Single Polymer Dynamics for Molecular Rheology", Journal of Rheology, 62, 371-403 (2018).
  • S. Kumar, J. S. Katz, C. M. Schroeder, "Heterogeneous Drying and Non-monotonic Contact Angle Dynamics in Concentrated, Film-forming Latex Drops", Physical Review Fluids, 2, 114304 (2017).
  • B. Li, L. R. Valverde, F. Zhang, Y. Zhou, S. Li, Y. Diao, W. L. Wilson, C. M. Schroeder, "Macroscopic Alignment and Assembly of -conjugated Oligopeptides using Colloidal Microchannels", ACS Applied Materials & Interfaces, 9, 41586-41593 (2017).
  • J. P. Berezney, A. B. Marciel, C. M. Schroeder, O. A. Saleh, "Scale-dependent Sti ness and Internal Tension of a Model Brush Polymer", Physical Review Letters, 116, 127801 (2017).
  • K. W. Hsiao, J. Dinic, Y. Ren, V. Sharma, C. M. Schroeder, "Passive Non-linear Microrheology for Determining Extensional Viscosity", Physics of Fluids, 29 121603 (2017).
  • Y. Zhou, B. Li, S. Li, H. A. M. Ardoena, W. L. Wilson, J. D. Tovar, C. M. Schroeder, "Concentration- Driven Assembly and Sol-Gel Transition -Conjugated Oligopeptides", ACS Central Science, 3, 986- 994 (2017).
  • L. W. Cuculis and C. M. Schroeder, "Molecular Mechanisms for Genome Editing Proteins: Single Molecule Studies of TALEs and CRISPR/Cas9", Annual Review of Chemical and Biomolecular Engineering, 8, 577-597 (2017).
  • B. Li, S. Li, Y. Zhou, H. A. M. Ardona, L. R. Valverde, W. L. Wilson, J. D. Tovar, C. M. Schroeder, "Non-equilibrium Self-assembly of pi-conjugated Oligopeptides in Solution", ACS Applied Materials & Interfaces, 9, 3977-3984 (2017).
  • K. Hsiao, C. Sasmal, J. R. Prakash, C. M. Schroeder, "Direct Observation of DNA Dynamics in Semi-dilute Solutions in Extensional Flow", Journal of Rheology, 61, 151-167 (2017).
  • C. Sasmal, K. Hsiao, C. M. Schroeder, J. R. Prakash, "Parameter-free Prediction of DNA Dynamics in Planar Extensional Flow of Semi-dilute Solutions", Journal of Rheology, 61, 169-186 (2017).
  • Y. Zhou and C. M. Schroeder, "Transient and Average Unsteady Dynamics of Single Polymers in Large-amplitude Oscillatory Extension", Macromolecules, 49, 8018-8030 (2016).
  • D. J. Mai and C. M. Schroeder, "Single Polymer Dynamics of Topologically Complex DNA", Current Opinion in Colloid and Interface Science, 26, 28-40 (2016).
  • Y. Zhou and C. M. Schroeder, "Single Polymer Dynamics Under Large Amplitude Oscillatory Extension", Physical Review Fluids, 1, 053301 (2016).
  • L. W. Cuculis, Z. Abil, H. Zhao, C. M. Schroeder, "TALE Proteins Search DNA using a Rotationally Decoupled Mechanism", Nature Chemical Biology, 12, 831-837 (2016).
  • C. M. Schroeder, S. Koster, Y. Huang, "Emerging Investigators 2016: Discovery Science Meets Technology", Lab on a Chip, 16, 2974-2976 (2016).
  • A. Shenoy, C. V. Rao, C. M. Schroeder, "Stokes Trap for Multiplexed Particle Manipulation and Assembly Using Fluidics", Proceedings of the National Academy of Sciences, 113, 3976-3981 (2016).
  • 43. K. Hsiao, C. M. Schroeder, C. E. Sing, "Ring Polymer Dynamics Are Governed by a Coupling between Architecture and Hydrodynamic Interactions", Macromolecules, 49, 1961-1971 (2016).
  • D. T. Reilly, S. H. Kim, J. A. Katzenellenbogen, C. M. Schroeder, "Fluorescent Nanoconjugate Derivatives with Enhanced Photostability for Single Molecule Imaging", Analytical Chemistry, 87, 11048- 11057 (2015).
  • Y. Li, K. Hsiao, C.A. Brockman, D.Y. Yates, R.M. Robertson-Anderson, J.A. Korn eld, M.J. San Francisco, C. M. Schroeder, G. B. McKenna, "When Ends Meet: Circular DNA Stretches Differently in Elongational Flows", Macromolecules, 48, 5997-6001 (2015).
  • X. Li, C. M. Schroeder, K. D. Dorfman, "Modeling the Stretching of Wormlike Chains in the Presence of Excluded Volume", Soft Matter, 11, 5947-5954 (2015).
  • L. W. Cuculis, Z. Abil, H. Zhao, C. M. Schroeder, "Direct Observation of TALE Protein Dynamics Reveals a Two-state Search Mechanism", Nature Communications, 6, 7277, DOI: 10.1038/ncomms8277 (2015).
  • R. Mohan, C. Sanpitakseree, A. V. Desai, S. E. Sevgen, C. M. Schroeder, P. J. A. Kenis, "A Microfluidic Approach to Study the Effect of Bacterial Interactions on Antimicrobial Susceptibility in Polymicrobial Cultures", RSC Advances, 5, 35211-35223 (2015).
  • D. Mai, A. B. Marciel, C. E. Sing, C. M. Schroeder, "Topology-Controlled Relaxation Dynamics of Single Branched Polymers", ACS Macro Letters, 4, 446-452 (2015).
  • A. B. Marciel, D. J. Mai, C. M. Schroeder, "Template-directed Synthesis of Structurally De ned Branched Polymers", Macromolecules, 48, 1296-1303 (2015).
  • A. Mukherjee and C. M. Schroeder, "Flavin-based Fluorescent Proteins: Emerging Paradigms in Biological Imaging", Current Opinion in Biotechnology, 31, 16-23 (2015).
  • A. Shenoy, M. Tanyeri, C. M. Schroeder, "Characterizing the Performance of the Hydrodynamic Trap Using a Control-based Approach", Microfluidics and Nanofluidics, 18, 1055-1066, (2015).
  • A. Mukherjee, K. B.Weyant, J.Walker, U. Agrawal, I. Cann, C. M. Schroeder, "Engineering and Characterization of New LOV-based Fluorescent Proteins from Chlamydomonas reinhardtii and Vaucheria frigida", ACS Synthetic Biology, 4, 371-377 (2015).
  • F. Latinwo, K. Hsiao, and C. M. Schroeder, "Nonequilibrium Thermodynamics of Dilute Polymer Solutions in Flow", Journal of Chemical Physics, 141, 174903 (2014).
  • E. M. Johnson-Chavarria, U. Agrawal, M. Tanyeri, T. E. Kuhlman, C. M. Schroeder, "Automated Single Cell Microbioreactor for Monitoring Intracellular Dynamics and Cell Growth in Free Solution", Lab on a Chip, 14, 2688-2697 (2014).
  • K. S. Lee, A. B. Marciel, A. G. Kozlov, C. M. Schroeder, T. M. Lohman, T. Ha, "Ultrafast Redistribution of E. coli SSB Along Long Single-Stranded DNA via Intersegment Transfer", Journal of Molecular Biology, 426, 2413-2421(2014).
  • F. Latinwo and C. M. Schroeder, "Determining Elasticity from Single Polymer Dynamics", Soft Matter, 10, 2178-2187 (2014).
  • A. B. Marciel, M. Tanyeri, B. D. Wall, J. D. Tovar, C. M. Schroeder, W. L. Wilson, "Fluidic-directed Assembly of Aligned Oligopeptides with -conjugated Cores", Advanced Materials, 25, 6398-6404 (2013).
  • F. Latinwo and C. M. Schroeder, "Nonequilibrium Work Relations for Polymer Dynamics in Dilute Solutions", Macromolecules, 46, 8345-8355 (2013).
  • M. Tanyeri and C. M. Schroeder, “Manipulation and Confinement of Single Particles using a Fluid Flow”, Nano Letters, 13, 2357-2364 (2013).
  • R. Mohan, A. Mukherjee, S. E. Sevgen, C. Sanpitakseree, J. Lee, C. M. Schroeder, P. J. A. Kenis, “A Multiplexed Microfluidic Platform for Rapid Antibiotic Susceptibility Testing”, Biosensors and Bioelectronics, 49, 118-125 (2013).
  • A. Mukherjee, J. Walker, K. B. Weyant, C. M. Schroeder, “Characterization of Flavin-based Fluorescent Proteins: An Emerging Class of Powerful Fluorescent Reporters”, PLOS ONE, 8, e64753 (2013).
  • U. Agrawal, D. Reilly, C. M. Schroeder, “Zooming in on Biological Processes with Fluorescence Nanoscop”, Current Opinion in Biotechnology, 24 (2013).
  • A. B. Marciel and C. M. Schroeder, “New Directions in Single Polymer Dynamics”, Journal of Polymer Science: Polymer Physics, 51, 556-566 (2013).
  • Y. Kim, S. Kim, M. Tanyeri, J. A. Katzenellenbogen, C. M. Schroeder, “Dendrimer Probes for Enhanced Photostability and Localization in Fluorescence Imaging”, Biophysical Journal, 104, 1566-1575 (2013).
  • A. Mukherjee and C. M. Schroeder, “Directed Evolution of Bright Mutants of a Flavin-Dependent Anaerobic Fluorescent Protein from Pseudomonas putida”, Journal of Biological Engineering, 6, 20, (2012).
  • Y. Kim, S. Kim, J. A. Katzenellenbogen, C. M. Schroeder, “Specific Labeling of Zinc Finger Proteins using Noncanonical Amino Acids and Copper-free Click Chemistry”, Bioconjugate Chemistry, 23, 1891-1901 (2012).
  • M.-H. Lai, J. H. Jeong, R. Devolder, C. A. Brockman, C. M. Schroeder, H. Kong, “Ellipsoidal Polyaspartamide Polymersomes with Enhanced Cell-Targeting Ability”, Advanced Functional Materials, 22, 3239-3246 (2012).
  • D. J. Mai, C. A. Brockman, C. M. Schroeder, “Microfluidic Systems for Single DNA Dynamics”, Soft Matter, 8, 10560-10572 (2012).
  • M. Tanyeri, M. Ranka, N. Sittipolkul, C. M. Schroeder, "Microfluidic Wheatstone Bridge for Rapid Sample Analysis", Lab on a Chip, 11, 4181-4186 (2011).
  • F. Latinwo and C. M. Schroeder, "Model Systems for Single Molecule Polymer Dynamics", Soft Matter, 7, 7907-7913 (2011).
  • M. Tanyeri, M. Ranka, N. Sittipolkul, C. M. Schroeder, "A Microfluidic-based Hydrodynamic Trap: Design and Implementation", Lab on a Chip, 11, 1786-1794 (2011).
  • C. A. Brockman, S. Kim, C. M. Schroeder, "Direct Observation of Single Flexible Polymers using Single Stranded DNA", Soft Matter, 7, 8005-8012 (2011).
  • B. Schudel, M. Tanyeri, C. M. Schroeder, P. J. A. Kenis, "Multiplexed Detection of Nucleic Acids in a Combinatorial Screening Chip", Lab on a Chip, 11, 1916-1923 (2011).
  • M. Tanyeri, E. M. Johnson-Chavarria and C. M. Schroeder, "Hydrodynamic Trap for Single Particles and Cells", Applied Physics Letters, 96, 224101 (2010).
  • S. Kim, C. M. Schroeder, X. S. Xie, "Single Molecule Observation of HIV-1 Reverse Transcriptase Polymerization Dynamics on Flow Stretched DNA Templates", Journal of Molecular Biology, 395, 995-1006 (2010).
  • Y. Han, D. Dodd, C. M. Schroeder, R. I. Mackie, I. K. O. Cann, “Comparative Analysis of Two Thermophilic Enzymes Exhibiting both β-1,4-Mannosidic and β-1,4-Glucosidic Cleavage Activities from Caldanaerobius polysaccharolyticus”, Journal of Bacteriology, 192, 4111-4121 (2010).
  • S. Kim, P.C. Blainey, C.M. Schroeder, and X.S. Xie, "Multiplexed Single-molecule Assay for Weak Enzymatic Activity on Flow-stretched DNA," Nature Methods, 4, 397-399 (2007).
  • C.M. Schroeder, P.C. Blainey, S. Kim, X.S. Xie, "Hydrodynamic Flow-stretching Assay for Single Molecule Studies of Nucleic Acid-Protein Interactions," in Single Molecule Techniques: A Laboratory Manual, T. Ha and P. Selvin (eds.), Cold Spring Harbor Laboratory Press (2007).
  • C.M. Schroeder, R.E. Teixeira, E.S.G. Shaqfeh, S. Chu, "Characteristic Periodic Motion of Polymers in Shear Flow," Physical Review Letters, 95, 018301 (2005).
  • C.M. Schroeder, H.P. Babcock, E.S.G. Shaqfeh, S. Chu, "Observation of Polymer Conformation Hysteresis in Extensional Flow," Science, 301, 1515-1519 (2003).

Articles in Conference Proceedings

  • C. M. Schroeder, D. J. Mai, Y. Zhou "Single Molecule Studies of Branched Polymers and Large Amplitude Oscillatory Extension (LAOE)", International Congress on Rheology, Kyoto, Japan, August 2016.
  • C. M. Schroeder, C. A. Brockman, F. Latinwo, "New Directions in Single Polymer Dynamics: Designer Macromolecules and Jarzynski Analysis for Materials Properties", International Congress on Rheology, Lisbon, Portugal, August 2012.
  • B. R. Schudel, M. Tanyeri, C. M. Schroeder, P. J. A. Kenis, "Fluorescence Microscopy for Detection of Molecular Beacons in a Multiplexed Microfluidic Device", Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), Jeju, Korea, November 2009.
  • C. M. Schroeder, E. S. G. Shaqfeh, R. E. Teixeira, S. Chu,"Non-equilibrium Behavior of DNA Molecules in Flows of Dilute and Concentrated Solutions", Proceedings of the XIVth International Congress on Rheology, Edited by The Korean Society of Rheology, Seoul, Korea, August 2004.

Pending Articles

  • S. Li, H. Yu, B. Li, J. S. Moore, C. M. Schroeder, \Regulating Charge Transport via Electric Field- Induced Reactions in Single Oligophenyl Junctions", submitted (2021).
  • C. D. Young, Y. Zhou, C. M. Schroeder, C. E. Sing, \Dynamics and Rheology of Ring-Linear Blend Semidilute Solutions in Extensional Flow: Modeling and Molecular Simulations", submitted (2021). arXiv: 2011.01386
  • Y. Zhou, C. D. Young, K. E. Regan, M. Lee, S. Banik, D. Kong, G. B. McKenna, R. M. Robertson- Anderson, C. E. Sing, C. M. Schroeder, \Dynamics and Rheology of Ring-Linear Blend Semidilute Solutions in Extensional Flow: Single Molecule Experiments", submitted (2021). arXiv: 2101.01222
  • C. Lin, D. Kumar, C. Richter, S. Wang, C. M. Schroeder, V. Narsimhan, \Vesicle Dynamics in Large Amplitude Oscillatory Extensional Flow", submitted (2021). arXiv: 2102.09097
  • C. Pan*, S. K. Tabatabaei*, S. M. H. Tabatabaei Yazdi, A. G. Hernandez, C. M. Schroeder*, O. Milenkovic*, \Rewritable Two-Dimensional DNA-Based Data Storage with Machine Learning Reconstruction", submitted (2021). bioRxiv: DOI: 10.1101/2021.02.22.432304

Invited Lectures

  • Single Polymer Dynamics for Molecular Rheology: Rings, Branches, and Entanglements
  • Automated Flow Control for Colloidal and Molecular Rheology
  • Single Polymer Dynamics for Molecular Rheology: Rings, Branches, and Entanglements
  • Watching the Molecular Dance of Rings and Branched Polymers using Single Molecule Imaging
  • Single Polymer Dynamics and Molecular Rheology of Ring Polymers
  • Single Polymer Dynamics and Molecular Rheology of Ring Polymers
  • Self-assembly and Single Molecule Charge Transport in Conjugated Organic Materials
  • Self-assembly and Single Molecule Charge Transport in Conjugated Organic Materials
  • elf-assembly and Single Molecule Charge Transport in Conjugated Organic Materials
  • Non-equilibrium Dynamics of Vesicles in Flow using a Stokes Trap
  • Dynamic Heterogeneity in Ring-Linear Polymers Revealed by Single Molecule Techniques
  • Recent Advances in Ring Polymer Dynamics: Development of New Chemistries for Pure Ring Systems
  • Self-assembly and Single Molecule Electronics of pi-conjugated Peptides
  • Non-equilibrium Dynamics of Vesicles in Precisely Controlled Flows using a Stokes Trap
  • Optically and Electronically Active Self-assembled pi-conjugated Peptides
  • Dynamic Heterogeneity in Single Polymer Dynamics and TALE Protein Search on DNA
  • Design and Engineering of Materials for Bioorganic Electronics: Supramolecular Assembly and Single Molecule Charge Transport
  • An On-Chip Nanoscale Storage System Using Chimeric DNA
  • Design and Engineering of Biohybrid Materials for Organic Electronics: From Supramolecular Assembly to Single Molecule Charge Transport
  • The Interview and Negotiation Process
  • Direct Observation of TALE Protein Dynamics on DNA: Non-specifi c Search and Specific Binding
  • Single Polymer Dynamics of Architecturally Complex Materials: Combs, Rings, Entanglements, Oh My!
  • Direct Observation of TALE(N) Protein Dynamics on DNA
  • Single Polymer Dynamics of Architecturally Complex Materials: Combs, Entanglements, and Self-Assembly
  • Single Polymer Dynamics in Semi-dilute Unentangled Solutions: From Molecular Conformation to Normal Stress
  • Stokes Trap: Applications to Colloids, Vesicles, and Single Polymer Dynamics
  • Single Polymer Dynamics of Comb, Ring, and Entangled Polymers
  • Single Polymer Dynamics and Applications of the Stokes Trap
  • Directed Assembly and Microrheology of Synthetic -conjugated Oligopeptides
  • Single Polymer Dynamics of Comb, Ring, and Entangled Polymers
  • A Molecular View of Soft Matter Dynamics
  • Single Polymer Dynamics in Large Amplitude Oscillatory Extension
  • Single Molecule Studies of Topologically Complex Polymers
  • Single Molecule Studies of Topologically Complex Polymers
  • Stokes Trap: Multiplexed Particle Manipulation and Assembly using Fluidics
  • Single Molecule Studies of Topologically Complex Polymers
  • Single Molecule Studies of Topologically Complex Polymers
  • Stokes Trap: Multiplexed Trapping of Particles and Molecules
  • New Frontiers in Single Polymer Dynamics: Branched Polymers, Complex Topologies, and Semi-dilute Solutions
  • New Frontiers in Single Polymer Dynamics and Fluidic-directed Assembly
  • Non-equilibrium Work Relations for Polymer Dynamics
  • Non-equilibrium Work Relations for Polymer Physics: A Tutorial for Practical Use in Polymer Dynamics
  • New Frontiers in Single Polymer Dynamics and Fluidic-directed Assembly of Soft Materials
  • New Frontiers in Single Polymer Dynamics and Microfluidic Assembly of Soft Materials
  • Advanced in Fluorescent Probes and Microfluidic Systems for Molecular Biophysics
  • New Frontiers in Single Polymer Dynamics and Microfluidic Assembly of Soft Materials
  • New Frontiers in Single Polymer Dynamics and Microfluidic Assembly of Soft Materials
  • New Frontiers in Single Polymer Dynamics and Microfluidic Assembly of Soft Materials
  • New Frontiers in Single Polymer Dynamics and Microfluidic Assembly of Soft Materials
  • Advances in Molecular Probes and Microfluidic Systems for Molecular Biophysics
  • Advanced Molecular Probes for Super-resolution Imaging
  • New Frontiers in Single Polymer Dynamics and Molecular Probe Engineering for Super-resolution Imaging
  • New Directions in Single Polymer Dynamics: Molecular Rheology, Hybrid Biomaterials, and Microfluidic Trapping",
  • New Directions in Single Polymer Dynamics: Molecular Rheology, Hybrid Biomaterials, and Microfluidic Trapping",
  • New Directions in Single Polymer Dynamics: Hybrid Biomaterials, Microfluidic Trapping, and Molecular Rheology
  • Single Cell Analysis via Microfluidic Trapping and Advances in Biological Imaging
  • New Directions in Single Polymer Dynamics: Hybrid Biomaterials, Microfluidic Trapping, and Molecular Rheology
  • New Frontiers in Single Polymer Dynamics and Molecular Probe Engineering for Super-resolution Imaging
  • New Frontiers in Single Polymer Dynamics and Molecular Probe Engineering for Super-resolution Imaging
  • Molecular Engineering for Advanced Biological Imaging and Soft Materials Dynamics", Packard Fellows Meeting
  • A Molecular Engineering Approach to Biological Imaging: From Polymers to Fluorescent Proteins to New Fluorescent Probes
  • Single Cell & Single Molecule Studies in Engineering: From Polymer Dynamics to Biological Systems
  • Single Cell & Single Molecule Studies in Engineering: From Polymer Dynamics to Biological Systems
  • Single Cell & Single Molecule Studies in Engineering: From Polymer Dynamics to Biological Systems
  • Polymer Dynamics at the Single Molecule Level
  • Single Molecule Studies of HIV-1 Reverse Transcriptase and Nucleic Acid Interactions
  • Single Molecule Studies of HIV-1 Reverse Transcriptase and Nucleic Acid Interactions
  • Single Molecule Studies of Protein Collisions & HIV-1 Reverse Transcriptase
  • Single Molecule Studies in Polymer Physics and Biology
  • Single Molecule Studies of DNA Replication and Polymer Physics
  • Single Molecule Studies of DNA Replication and Polymer Physics
  • Single Molecule Studies of DNA Replication and Polymer Physics
  • Single Molecule Studies of DNA Replication and Polymer Physics
  • Single Molecule Studies of DNA Replication and Polymer Physics
  • Single Molecule Studies of DNA Replication and Polymer Physics
  • Single Molecule Studies of DNA Replication and Polymer Physics
  • Single Molecule Studies of DNA Replication and Polymer Physics
  • DNA Manipulation at the Single Molecule Level
  • Configuration Hysteresis in Polymer Extension

Patents

  • O. Milenkovic, C. M. Schroeder, H. Tabatabaei, K. Tabatabaei, A. Hernandez, C. Pan, \DNA Based Image Storage and Retrieval", United States Non-Provisional Patent, UIUC2019-195-02(US), 17/102,143, November 2020.
  • O. Milenkovic, N. Athreya, A. Khandelwal, J.-P. LeBurton, X. Li, C. M. Schroeder, K. Tabatabaei, B. Li, "On-Chip Nanoscale Storage System Using Chimeric DNA", United States Non-Provisional Patent, 19-1227-US, 16/593,450, October 2019.
  • Y. Kim, S. Kim, M. Tanyeri, J. A. Katzenellenbogen, C. M. Schroeder, "Dye-conjugated Dendrimers", United States Patent, No. 9,448,173, University of Illinois at Urbana-Champaign, September 2016.
  • C. M. Schroeder, H. P. Babcock, E. S. G. Shaqfeh, S. Chu, "System and Method for Con ning an Object to a Region of Fluid Flow Having a Stagnation Point", United States Patent, No. 7,013,739 B2, March 21, 2006.

Honors

  • Ray & Beverly Mentzer Professor, 2019
  • Society of Rheology Publication Award, 2019
  • Center for Advanced Study, Beckman Fellow, University of Illinois, 2014
  • Camille Dreyfus Teacher-Scholar Award, 2013
  • NSF CAREER Award, National Science Foundation, 2013
  • Dean's Award for Excellence in Research, University of Illinois, 2013
  • Arthur B. Metzner Early Career Award, Society of Rheology, 2012
  • U.S. Frontiers of Engineering, National Academy of Engineering, 2012
  • Packard Fellowship in Science and Engineering, 2011
  • Tomorrow's PIs, Genome Technology, 2008
  • List of Teachers Ranked as Excellent, University of Illinois, Spring 2011, Fall 2008
  • Pathway to Independence Award, National Institute of Health, 2006-2011
  • Postdoctoral Fellowship, Jane Coffin Childs Fund for Medical Research, 2005-2006
  • Gerald Lieberman Fellowship, Stanford University, 2003-2004
  • NSF Graduate Fellowship, National Science Foundation, 1999-2003
  • Stanford Graduate Fellow, Stanford University, 1999
  • University Honors, Carnegie Mellon University, 1998
  • Andrew Carnegie Scholar, Carnegie Mellon University, 1998
  • Phi Kappa Phi Honor Society, 1998
  • Donald F. Othmer Academic Excellence Award, AIChE

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