Ashok Samuel
Primary Research Area
- Biomedical imaging - Biophotonics
Research Areas
- Biophotonics
- Cancer
- Live-cell imaging
- Molecular imaging
- Tumor microenvironments
Education
- 2006-2012 Ph.D. Raman Spectroscopy, Polymer Chemistry, Physical Chemistry, Indian Institute of Science, Bangalore
Academic Positions
- 2023 - Present. Research Associate Professor, Department of Bioengineering, University of Illinois Urbana Champaign (UIUC), USA.
- 2017 - 2023. Assistant Professor (Research), Research Organization for Nano & Life Innovation, Waseda University, Tokyo, Japan
Research Interests
- Cancer Metastasis: Tumor aggressiveness, metabolic biomarkers and drug response
- Bioimages To Molecules: Biochemical-specific label-free live-cell imaging
- Interdisciplinary Solutions: Integrating optical imaging techniques
- 3D Tumor Spheroid Models: Phenotype-dependent drug responses in cancer
- Next-Generation Diagnostic Tools: Developing biochemically informed tissue diagnostics.
- Advanced Raman imaging: Biochemically Unique Cell Phenotypes
Primary Research Area
- Biomedical imaging - Biophotonics
Research Areas
- Biophotonics
- Cancer
- Live-cell imaging
- Molecular imaging
- Tumor microenvironments
Selected Articles in Journals
- Samuel, A. Z.,* Sugiyama, K., Takeyama, H. “Direct intracellular detection of biomolecule specific bound-water with Raman spectroscopy”. Spectrochim Acta A Mol. Biomol. Spectrosc. 2023.
- Samuel, A. Z.,* Sugiyama, K., Ando, M., Takeyama, H. “Direct imaging of intracellular RNA, DNA, and liquid-liquid phase separated membraneless organelles with Raman microspectroscopy”. Commun. Biol. 2022.
- Hur, S. W.; Kwon, M.; Manoharaan, R.; Mohammadi, M. H.; Samuel, A. Z.; Mulligan, M. P.; Hergenrother, P. J.; Bhargava, R. Capturing cell morphology dynamics with high temporal resolution using single-shot quantitative phase gradient imaging. J. Biomed. Opt. 2024
- Sivaguru, M.; Mori, S.; Fouke, K. W.; Ajijola, O. A.; Shivkumar, K.; Samuel, A.; Bhargava, R.; Fouke, B. W. Osteopontin stabilization and collagen containment slows amorphous calcium phosphate transformation during human aortic valve leaflet calcification. Sci. Rep. 2024
- Samuel, A. Z.,* “Direct estimation of polymer crystallinity with Raman spectroscopy using ratio of scattering cross-sections estimated from variable temperature measurements” Spectrochim. Acta A. 2020.
Honors
- Junior Research Fellowship, Council of Scientific and Industrial Research, India (2005)
- Dr. J. C. Ghosh medal, Indian Institute of Science, India (2013)
Research Honors
- Early Career Researcher Award, Society for Applied Spectroscopy, USA. (2013)