BIOE: Kristan S. Worthington - "Human Retinal Engineering using Induced Pluripotent Stem Cells and High-Resolution 3D Printing"

Speaker Kristan S. Worthington, Assistant Professor, Department of Biomedical Engineering, The University of Iowa, Iowa City
Date: 2/27/2018
Time: 11 a.m. - 12 p.m.

2240 Digital Computer Lab, 1304 W Springfield Avenue, Urbana, IL

Event Contact: Lisa Leininger

Department of Bioengineering

Event Type: Seminar/Symposium

BioE Big Ten Exchange Seminar


"Human Retinal Engineering using Induced Pluripotent Stem Cells and High-Resolution 3D Printing"



Recent advances in stem cell technology have paved the way for the production of patient-specific neurons that are promising for the treatment of neurodegenerative diseases. In the case of retinal degeneration and associated photoreceptor cell therapy, polymer support scaffolds are critical for cellular survival and integration. In this talk, Kristan will discuss progress towards optimizing these biomaterials for the retina, including several strategies for controlling scaffold chemistry, structure and mechanics. Tailoring biomaterial properties for distinct tissue types will be considered, as will the use of emerging technologies such as two-photon polymerization. The findings she will present provide a foundation for using biomaterials to model retinal disease in the laboratory and to restore vision in the clinic.


About the Speaker:

Kristan Worthington is an assistant professor in the Department of Biomedical Engineering at The University of Iowa, where she and her group create tissue scaffolds for retinal regeneration. Her primary research interests also include stem cell fate engineering, precision drug delivery, and other photopolymerized biomaterials. She completed a postdoctoral fellowship at the Wynn Institute for Vision Research, a Ph.D. in chemical engineering from the University of Iowa, and M.S. & B.S. degrees in Biological Engineering from Utah State University.


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