BIOE: John Wilson - "Engineering Nanotechnologies for Immuno-Oncology"
(sign-up)Dr. John T Wilson, Assistant Professor, Departments of Chemical & Biomolecular Engineering and also Biomedical Engineering, Vanderbilt University, Nashville, TN
2310 Everitt Laboratory, 1406 W Green Street, Urbana
|Event Contact:||Lisa Leininger
Department of Bioengineering
“Engineering Nanotechnologies for Immuno-Oncology”
Cancer immunotherapy is revolutionizing the treatment of an ever-expanding diversity of cancer types, yielding impressive complete and durable responses in a subset of patients. However, the vast majority of patients do not respond to currently FDA approved immune checkpoint inhibitors. Our group is working to solve this emergent grand challenge in immuno-oncology through the development of molecularly engineered technologies that increase immune recognition of tumors. This talk will focus on our recent work in the design of self-assembled polymeric drug carriers that enhance the intracellular delivery and biological activity of diverse immunomodulatory cargo. Specifically, I will discuss our efforts to engineer pH-responsive materials for delivery of cancer vaccines and nucleic acid activators of the innate immune system, and describe how we are leveraging these materials to increase tumor immunogenicity and responses to immunotherapy.
About the Speaker:
John T. Wilson is an Assistant Professor of Chemical & Biomolecular Engineering at Vanderbilt University. Dr. Wilson graduated from Oregon State University with a B.S. in Bioengineering. He went on to earn his Ph.D. in Bioengineering at the Georgia Institute of Technology, followed by a postdoctoral fellowship in the field of Immunoengineering at the University of Washington. Dr. Wilson started his independent laboratory at Vanderbilt in January of 2014 where his lab brings together expertise in polymer chemistry, nanotechnology, and immunology to develop new immunotherapeutic technologies.
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