BIOE: Fan Lam - “Towards Ultrahigh-Resolution Metabolic Imaging of the Brain”

Speaker Fan Lam, Ph.D., Postdoctoral Fellow, Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign
Date: 1/25/2018
Time: 11:30 a.m. - 12:30 p.m.

2240 Digital Computer Lab, 1304 W Springfield Avenue, Urbana, IL

Event Contact: Lisa Leininger

Department of Bioengineering

Event Type: Seminar/Symposium

(Please note this seminar is on a Thursday and the start time is 11:30 a.m.)


“Towards Ultrahigh-Resolution Metabolic Imaging of the Brain”


Abstract: Brain mapping is one of the most exciting frontiers of contemporary science. While recent rapid development of neuroimaging technologies has enabled the visualization of detailed structural and functional organizations of the brain, molecular imaging of the brain has been a dream of many scientists and medical practitioners for several decades. Most existing molecular imaging techniques require introducing exogenous probes into the subject, limiting their in vivo translation. Magnetic resonance spectroscopic imaging (MRSI) has long been recognized as a powerful label-free molecular imaging tool. However, clinical and research applications of MRSI have been developing slowly due to several fundamental technical hurdles, including slow imaging speed, poor spatial resolution, low sensitivity and overwhelming nuisance signals from tissue water and lipids. In this talk, I will discuss our recent advances in tackling these challenges using a subspace imaging framework integrating novel signal encoding, decoding and quantitative analysis strategies. These developments have led to an ultrafast MRSI technology offering an unprecedented combination of speed, resolution and SNR, with more than an order of magnitude improvement over any existing method. I’ll give a brief overview of this new technology and discuss potential applications in addressing important clinical problems and neuroscience questions.


About the Speaker: Fan Lam received the B.S. degree in biomedical engineering from Tsinghua University, China, in 2008, and the Ph.D. degree in electrical and computer engineering (ECE) from the University of Illinois at Urbana-Champaign in 2015, where he is currently a Beckman Institute Postdoctoral Fellow. His research focuses on developing advanced magnetic resonance based neuroimaging technologies and their applications to the study of brain function at normal and diseased states.

Dr. Lam is a recipient of several awards, including the Junior Fellow Award from ISMRM (International Society of Magnetic Resonance in Medicine), the Best Student Paper Award from ISBI 2015 (International Symposium of Biomedical Imaging), a Beckman Institute Graduate Fellowship, and the Robert T. Chien Memorial Award from ECE, UIUC.



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